Abstract:Reductive leaching experiments of zinc anode slime were performed by using glucose as reductant. The effects of glucose concentration , sulfuric acid concentration, leaching temperature,, on the leaching ratio of Mn and Pb were investigated using response surface methodology for optimal and analysis. Optimal process parameters on Mn and Pb from zinc anode slime and the order polynomial equation of model were obtained. Under the optimal condition as follows, glucose concentration of 3.5g，sulfuric acid concentration of 16g，leaching temperature of 90℃. The results show that the theoretical leaching ratio of Mn and Pb of model predicts can reach 93.19% and 0.37 respectively.