Abstract:The raw ore of a lead-zinc ore contains Pb 1.67%, Zn 6.85% and S 16.22%. In production, the process of "lead-zinc sequential priority flotation and middling sequential return" is adopted. The production indexes are lead concentrate grade 50.69%, zinc content12.61%, lead recovery 75.53%, zinc concentrate grade 48.77%, lead content 1.59%, zinc recovery 73.91%.SThe content of lead and zinc is a little higher in zinc and lead concentrate and the zinc recovery is not ideal.SIn order to solve the problem, this paper at the scene of the understanding on the basis of the production process and the properties of the ore, detailed beneficiation process optimization test has been carried out on the lead-zinc mine, based on the part of the medicament system optimization, using the new efficient collector BK-LY11,as well as the zinc flotation circuit adopts the middlings grinding process, significantly improve the lead and zinc content, finally the lead and zinc concentrate indexes are improved and successfully practiced in production. The recoveries of lead and zinc improved by 5.83 and 8.46 percentage points respectively after optimization.